博士/教授/博导  西安交通大学教务处副处长

2007年毕业于上海交通大学，获生物化学与分子生物学博士学位，导师贺林教授（院士）。2007年7月起于西安交通大学医学部任职，主要从事：

1.精神疾病的分子机制研究；

2.先天性遗传疾病的分子变异研究。

现任中国医学生物化学与分子生物学会青年委员；中国遗传学会科普委员会委员；二十一种国际国内学术期刊审稿专家(Molecular Psychiatry, Schizophrenia Research, PLoS ONE, etc)；期刊World Journal of Meta-Analysis编委；国家自然科学基金委生命科学部基金评议人；交大医学部科技处兼职主管；教育部重点实验室学术秘书。

2013年入选教育部“新世纪优秀人才”支持计划。同年，公派访学赴美国加州大学圣地亚哥分校（UCSD）医学院从事科研和学习交流。

2015年7月起，经组织部任命，担任西安交通大学教务处副处长。

个人主页：http://medgs.xjtu.edu.cn/tearch/t_index.php?id=803

 

研究成果：

1. 科研项目  主持国家自然科学基金、陕西省国际科技合作重点项目等科研项目8项，参与国家自然科学基金、中国博士后科学基金等项目9项。

2. 获奖成果  2016年陕西省高等学校科学技术奖励一等奖

3. 发表各类学术论文60余篇。截止2016年3月，已在Molecular Psychiatry （近年最高影响因子：15.147）、Schizophrenia Research、Progress in Neuro-Psychopharmacology & Biological Psychiatry、American Journal of Medical Genetics Part B、PLoS ONE、Genomics等SCI收录期刊发表论文38篇，累计影响因子约128；其中以通讯作者或第一作者发表SCI论文23篇（IF>10的论文2篇），累计影响因子数约86。论文他引400余次，H因子=11（Google Scholar）。

 

代表性SCI收录论文：

* Corresponding author

1. 精神疾病研究

1)      Ma Jie, Lan Xi, Gao Ning, Wang Jin, Hao Dingjun, Yao Jianfeng, Huang Linhong, Valenzuela Robert, Zhang Rui*. A genetic association study between common variants in the ABCA13 gene and schizophrenia in a Han Chinese population. Psychiatry Research, 2013, 209(3):748-749. (SCI, IF: 2.682)

2)      Zhang Rui, Zhang Huan, Li Ming, Li Hongbo, Li Yue, Valenzuela K Robert, Su Bing, Ma Jie*. Genetic analysis of common variants in the CMYA5 (cardiomyopathy-associated 5) gene with schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2013, 46:64-69. (SCI, IF:4.025)

3)      Zhang Rui, Du Xiaoyun, Yu Jie, Xu Nan, Zheng Yuewen, Zhao Yaling, Zhang Huan, Ma Jie *. No genetic evidence for Neuregulin 3 conferring risk of schizophrenia in the Chinese population. Psychiatry Research, 2013, 205(3):279-281. (SCI, IF: 2.682)

4)      Zhang Rui, Yan Jidong, Valenzuela Robert K, Lu Shemin, Du Xiaoyun, Zhong Bo, Ren Juan, Zhao Sihai, Gao Chengge, Wang Lei, Guo Tingwei, Ma Jie*. Further evidence for the association of genetic variants of ZNF804A with schizophrenia and a meta-analysis for genome-wide significance variant rs1344706. Schizophrenia Research, 2012, 141(1):40-47. (SCI, IF: 4.426)

5)      Zhang Rui, Lu Shemin, Meng Liesu, Min Zixin, Tian Juan, Valenzuela Robert K, Guo Tingwei, Tian Lifang, Zhao Wenxiang, Ma Jie*. Genetic evidence for the association between the early growth response 3 (EGR3) gene and schizophrenia. PLoS ONE, 2012, 7(1):e30237. (SCI, IF: 3.534)

6)      Zhang Rui, Valenzuela Robert K, Lu She-Min, Meng Liesu, Guo Ting-Wei, Du Xiaoyun, Kang Wanhu, Ma Jie*. Is the conserved mammalian region of ZNF804A locus associated with schizophrenia? A population-based genetics analysis. Schizophrenia Research, 2011, 133(1-3):159-164. (SCI, IF: 4.426)

7)      Zhang R, Lu SM*, Qiu C, Liu XG, Gao CG, Guo TW, Valenzuela RK, Deng HW, Ma J*. Population-based and family-based association studies of ZNF804A locus and schizophrenia. Molecular Psychiatry, 2011, 16(4):360-361. (SCI, IF: 15.147)

8)      Zhong Nannan, Zhang Rui, Qiu Chuan, Yan Han, Valenzuela Robert K, Zhang Huan, Kang Wanghu, Lu Shemin, Guo Tingwei, Ma Jie*. A novel replicated association between FXYD6 gene and schizophrenia. Biochemical and Biophysical Research Communications, 2011, 405(1):118-121. (SCI, IF: 2.484)

9)      Zhang Rui, Zhong Nan-Nan, Liu Xiao-Gang, Yan Han, Qiu Chuan, Han Yan, Wang Wei, Hou Wei-Kun, Liu Yue, Gao Cheng-Ge, Guo Ting-Wei*, Lu She-Min, Deng Hong-Wen, Ma Jie*. Is the EFNB2 locus associated with schizophrenia? Single nucleotide polymorphisms and haplotypes analysis. Psychiatry Research, 2010, 180(1):5-9. (SCI, IF: 2.682)

10)   Ma Jie, Li Dong-Min, Zhang Rui, Yang Xu-Dong, Lu She-Min, Gao Cheng-Ge, Wu Sheng-Nan, Wang Lei. Genetic analysis of glutamate cysteine ligase modifier (GCLM) gene and schizophrenia in Han Chinese. Schizophrenia Research, 2010,119(1-3):273-274. (SCI, IF: 4.426)

11)   Ma Jie, Sun Jian, Zhan Huan, Zhang Rui, Kang Wan-Hu, Gao Cheng-Ge, Liu Hai-Sheng, Ma Xue-Hong, Min Zi-Xin, Zhao Wei-Xiang, Ning Qi-Lan, Wang Shu-Hong, Zhang Yin-Cang, Guo Ting-Wei, Lu She-Min*. Evidence for transmission disequilibrium at the DAOA gene locus in a schizophrenia family sample. Neuroscience Letters, 2009, 462(2):105-108. (SCI, IF: 2.105)

12)   Ma Jie, Fan Jin-Bo, Bian Li, Zhang Chang-Shun, Li Xing-Wang, Gu Niu-Fan, Feng Guo-Yin, Clair David St, He Lin*. Association studies of a (TG)n dinucleotide repeat at Chromosome 15q13.3 and schizophrenia in the Chinese population. Psychiatry Research, 2008,159(1-2):245-249. (SCI, IF: 2.682)

13)  Ma J, Qin W, Wang XY, Guo TW, Bian L, Duan SW, Li XW, Zou FG, Fang YR, Fang JX, Feng GY, Clair SD, He L. Further evidence for the association between G72/G30 genes and schizophrenia in two ethnically distinct populations. Molecular Psychiatry, 2006,11(5):479-487. (SCI, IF: 15.147)

 

2. 先天性遗传疾病研究

1)      Daxu Li, Ran Xu, Fumeng Huang, Biyuan Wang, Yu Tao, Zijian Jiang, Hairui Li, Jianfeng Yao, Peng Xu, Xiaokang Wu, Le Ren, Rui Zhang*, John R Kelsoe, Jie Ma*. A novel missense mutation in collagenous domain of EDA gene in a Chinese family with X-linked hypohidrotic ectodermal dysplasia. Journal of Genetics, 2015,94(1):115-119. (SCI, IF: 1.013)

2)      Liu Xudong, Gao Linghan, Zhao Aman, Zhang Rui, Ji Baohu, Wang Lei, Zheng Yonglan, Zeng Bingfang, Valenzuela Robert, He Lin*, Ma Jie*. Identification of duplication downstream of BMP2 in a Chinese family with brachydactyly type A2 (BDA2). PLoS ONE, 2014, 9(4):e94201. (SCI, IF: 3.534)

3)      Li Daxu, Du Xiaoyun, Zhang Rui, Shen Bo, Huang Yanli, Valenzuela Robert K, Wang Bin, Zhao Huaxiang, Liu Zunwei, Li Jianjun, Xu Zhao, Gao Linghan*, Ma Jie*. Mutation identification of the DSPP in a Chinese family with DGI-II and an up-to-date bioinformatic analysis. Genomics. 2012,99(4):220-226. (SCI, IF: 2.793)

 

3. 骨科疾病研究

1)      Rui Zhang, Jianfeng Yao*, Peng Xu, Baohu Ji, James V Luck, Brian Chin, Shemin Lu, John R Kelsoe, Jie Ma*. A comprehensive meta-analysis of association between genetic variants of GDF5 and osteoarthritis of the knee, hip and hand. Inflammation Research, 2015, 64(6):405-414. (SCI, IF: 2.142)

2)      Rui Zhang, Jianfeng Yao*, Peng Xu, Baohu Ji, Géraldine Voegeli, Weikun Hou, Hui Li, Yi Wang, John R Kelsoe, Jie Ma*. Association between genetic variants of DVWA and osteoarthritis of the knee and hip: a comprehensive meta-analysis. International Journal of Clinical and Experimental Medicine. 2015, 8(6):9430-9437. (SCI, IF: 1.277)

3)      Zhang Rui, Ma Jie, Yao Jianfeng*. Molecular mechanisms of the cartilage specific microRNA-140 in osteoarthritis. Inflammation Research, 2013,62(10):871-877. (SCI, IF: 2.142)

 

教学与人才培养:

在读博士研究生2人，硕士研究生1人。已毕业硕士研究生1人，该生先后获得“光华奖学金”奖励、优秀研究生、优秀毕业生等表彰。学习期间，该生的研究课题获医学研究生自主创新实验项目资助（台湾光华教育基金会）。协助培养博士、硕士研究生多人，其中1人因科研成绩突出获得2010年“博士研究生学术新人奖”奖励（中国教育部）和西安交通大学校级优秀博士论文表彰。

已指导国家级、省级等各类大学生科研创新项目共11项，先后完成对41人次的指导和培养工作。其中，王彬、焦李子、黄芙萌、李海瑞等学生作为我校医学部学生代表相继参加“第二届、第三届全国大学生基础医学创新论坛暨实验设计大赛”，获得二等奖、三等奖和优秀奖各1项。