杨旭东,讲师,生物化学与分子生物学博士。研究方向为哮喘的分子机制。主持国家自然科学基金面上项目1项,发表SCI论文多篇。
教育经历:
2003.9-2011.3 西安交通大学,生命学院, 博士, 导师:吕社民教授
1999.9-2002.7 西安交通大学,病源生物学系, 硕士 , 导师:鲍德虎教授
1991.9-1995.7 中山大学, 生物化学系, 学士,
工作经历:
1995.7-至今 西安交通大学,医学部基础医学院生物化学与分子生物学系
主持的项目:血管心外膜活性物质(BVES)在哮喘导致的气道上皮损伤中的作用研究(项目编号:81370123,执行时间:2014.1-2014.12, 经费:16万元)
代表性论文:
1: Liu L, Sun Q, Bao R, Roth M, Zhong B, Lan X, Tian J, He Q, Li D, Sun J, Yang
X, Lu S. Specific regulation of PRMT1 expression by PIAS1 and RKIP in BEAS-2B
epithelia cells and HFL-1 fibroblasts in lung inflammation. Sci Rep. 2016 Feb
25;6:21810. doi: 10.1038/srep21810.
2: Sun Q, Liu L, Roth M, Tian J, He Q, Zhong B, Bao R, Lan X, Jiang C, Sun J,
Yang X, Lu S. PRMT1 Upregulated by Epithelial Proinflammatory Cytokines
Participates in COX2 Expression in Fibroblasts and Chronic Antigen-Induced
Pulmonary Inflammation. J Immunol. 2015 Jul 1;195(1):298-306. doi:
10.4049/jimmunol.1402465.
3: Sun Q, Yang X, Zhong B, Jiao F, Li C, Li D, Lan X, Sun J, Lu S. Upregulated
protein arginine methyltransferase 1 by IL-4 increases eotaxin-1 expression in
airway epithelial cells and participates in antigen-induced pulmonary
inflammation in rats. J Immunol. 2012 Apr 1;188(7):3506-12. doi:
10.4049/jimmunol.1102635.
4: Yang X, Sun Q, Asim MB, Jiang X, Zhong B, Shahzad M, Zhang F, Han Y, Lu S.
Nitric oxide in both bronchoalveolar lavage fluid and serum is associated with
pathogenesis and severity of antigen-induced pulmonary inflammation in rats. J
Asthma. 2010 Mar;47(2):135-44. doi: 10.3109/02770900903483808.